hrp0089p1-p034 | Bone, Growth Plate & Mineral Metabolism P1 | ESPE2018

Is Plasma C-Type Natriuretic Peptide Level Available for Typing and Diagnosis of Skeletal Dysplasia Cases?

Kizilcan Cetin Sirmen , Goksen Damla , Ozen Samim , Alper Hudaver , Isık Esra , Onay Huseyin , Darcan Sukran

Introduction: Skeletal dysplasia is a heterogeneous group of disease, leading to abnormal enchondral ossification and typing of the disease is quite complex. C-type natriuretic peptide (CNP), one of the members of the natriuretic peptide family, has been implicated to play a role in bone development. CNP levels were high in some types of the skeletal dysplasia.Objective: The aim of this study is to evaluate the possibility of using CNP, as a marker for s...

hrp0094p2-69 | Bone, growth plate and mineral metabolism | ESPE2021

Evaluation of Admission Characteristics, Treatment and Follow-up Findings of Children with Primary Osteoporosis

Kizilcan Cetin Sirmen , Siklar Zeynep , Aycan Zehra , Ozsu Elif , Ceran Aysegul , Senyazar Gizem , Karaca Seda Erisen , Berberoglu Merih ,

Introduction: Primary osteoporosis (POP) is a rare and important problem in childhood that can cause serious skeletal deformities and morbidity. In this study, we aimed to reveal the spectrum of POP in childhood, and also to assess the effectiveness and safety of bisphosphonates in increasing BMD, reducing fractures, and improving quality of life.Method: Patients with POP and who received at least one course of pamidrona...

hrp0094p2-89 | Bone, growth plate and mineral metabolism | ESPE2021

Clinical Profile of Parathyroid Adenoma in Children and Adolescents: A single-center experience

Kizilcan Cetin Sirmen , Siklar Zeynep , Ozsu Elif , Aycan Zehra , Ceran Aysegul , Karaca Seda Erisen , Senyazar Gizem , Berberoglu Merih ,

Introduction: Parathyroid adenoma (PRAD) is less common than in adulthood, but its morbidity is higher in children. The typical presentation is incidentally discovered as asymptomatic hypercalcemia. We aimed to evaluate the clinical characteristics of PRAD and our clinical experience since the early disease is often asymptomatic.Method: From 2010-2020, all children diagnosed with PRAD at our institution ...